disease are the most

Those patients with very high degrees of disability at the beginning of the disease are the most easily identified as having a worse prognosis, and not those with intermediate values. In most studies, although not all, the existence of early erosive disease usually predicts a more severe evolution of the disease, especially in terms of greater progression of structural damage.

Patients with greater activity of synovitis measured by the number of inflamed joints or compound indices of activity (Ritchie, Disease Activity Score, Hondrocream, etc.) usually have a worse prognosis.